Drinks or foods with high fructose corn syrup may increase risk of type 2 diabetes mellitus and cardiovascular disease, according to a new animal study.
The study by A. Sheludiakova of University of Sydney in Sydney, Australia and colleagues found rats drinking sugary beverages got more abdominal fat, higher levels of triglycerides, and developed impaired insulin/glucose homeostasis, compared to those drinking water, even though the former did not gain more weight than the latter.
The researchers gave Male Hooded Wister rats free access to a drink with 10 percent sucrose or a 10 percent fructose/glucose (50/50) drink or water as controls in addition to a normal diet for 56 days, which is equivalent to four years for humans. Wister rats live an average of 3.1 years.
At the end of the dietary intervention, they measured metabolic parameters including triglycerides in the blood, liver triglycerides, abdominal fat, and oral glucose tolerance.